Izmirian with an "e"

I have recieved some very brief and exciting news that brings me one step closer. I have recieved an email from William Izmerian. William is the son of Anania and lives in the USA. The first thing I find interesting is he spells his surname differently. We know William is a direct relative so there is no issue about being from different family. If this happened in the 1920's imagine what it was like in the 1600's 1700's and 1800's especially in less educated communities.